We have recently stayed here as Venice is close to our Prosecco Hills holiday and an obvious stopover.
The hotel is 3 star and family owned, run by Elena. It is within easy walking distance of everything and a great spot to base yourself. There is a private garden where you can stroll or just sit to escape any hustle and bustle.
The hotel can arrange ferries/shuttle buses to Marco Polo Airport. They can also arrange local guides.
Breakfast is served on their garden terrace (weather permitting) and their is a min bar in your room for quiet evenings.
This is our stopover choice for Venice.